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Using a
computer-assisted counting technique (known as stereological assessment), the
researchers compared the numbers of discrete brain cell populations in the
medicated vs. unmedicated monkeys.
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Both of the
antipsychotic drugs resulted in the loss of brain cells from the parietal
lobe. More specifically, the numbers
of neurons and glia (astrocytes and oligodendrocytes) were all significantly
reduced.
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Review of Brain
Cells
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neuron = a nerve
cell that makes, absorbs, stores, and releases chemicals
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oligodendrocyte = a
type of glial cell which produces myelin, the lipid-containing insulation
layer which surrounds neurons and enhances the speed of cell-to-cell
communication
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astrocyte = a type
of glial cell which performs many functions, including the synthesis,
release, and reuptake of brain chemicals; and the provision of structural
support, detoxification, nourishment, and “housekeeping” functions (clearing
away dead or waste material)
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