Using a computer-assisted counting technique (known as stereological assessment), the researchers compared the numbers of discrete brain cell populations in the medicated vs. unmedicated monkeys.

Both of the antipsychotic drugs resulted in the loss of brain cells from the parietal lobe.  More specifically, the numbers of neurons and glia (astrocytes and oligodendrocytes) were all significantly reduced.






Review of Brain Cells

neuron = a nerve cell that makes, absorbs, stores, and releases chemicals

oligodendrocyte = a type of glial cell which produces myelin, the lipid-containing insulation layer which surrounds neurons and enhances the speed of cell-to-cell communication

astrocyte = a type of glial cell which performs many functions, including the synthesis, release, and reuptake of brain chemicals; and the provision of structural support, detoxification, nourishment, and “housekeeping” functions (clearing away dead or waste material)