| Postmortem Studies of Humans |
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| 1988 Buhl and
Bojsen-Moller – 100 patients (consecutive autopsies) |
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| schizophrenia 35% Alz. pathology |
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| non-psych controls 0% Alz. pathology |
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| 1989 | Soustek – 225 pts with chronic
schizophrenia (dying in 1975-85) |
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| 41%
showed Alz. pathology |
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| 6x higher rate than general
population |
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| 1994 Wisniewski –
102 patients with history of schizophrenia |
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| 41 died prior to
antipsychotic era 46% had tangles |
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| 62 died after
antipsychotic era 74% had tangles |
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