The defining features of Alzheimer’s disease include (but are not limited to):

1)abnormal deposits inside neurons (composed of a protein known as “tau”, these are sometimes referred to as neurofibrillary tangles]

2)abnormal deposits outside neurons (composed of a protein known a
      beta-amyloid, these deposits are referred to as amyloid plaques)

3)  the disintegration and death of neurons


This slide depicts Alzheimer’s abnormalities as they would appear through the
lens of a microscope.  The pink cells (top center, lower right) are neurons.  An
amyloid plaque can be seen in the lower left.  Tau tangles appear inside the
large neuron (dark blue).  Disintegrating cell parts (microtubules) appear in
white.