Recall from slide #38 that 70% of all dementias in the U.S.A. are attributed to Alzheimer’s disease (AD).
	These pictures show the locations of abnormal tissue in the human brain as Alzheimer’s disease begins (top) and progresses (bottom).
	Top:   pathology begins within the hippocampus of the temporal lobe
	Bottom:   in advanced disease, Alzheimer’s pathology extends well beyond    the temporal lobe.   The hippocampus undergoes profound    degeneration.  Fluid-filled spaces of the  brain (known    as    ventricles) become enlarged.