If antipsychotic
drugs are causally related to Alzheimer’s pathology, it would be important
for medical doctors and researchers to discern which anatomic abnormalities
they potentially induce.
It is in this
context that a recent discovery in neuroscience is most pertinent.Using electron microscopy to investigate
the smallest components of brain cells, a team of investigators at the
University of Pittsburgh (Desai et al, 2005)identified apolipoprotein D as a core component within the
beta-amyloid deposits (plaques) which distinguish Alzheimer’s disease.
